Dr. Atsuko Chiba is a research psychologist who uses a device called the DC Mini to enter her patients' dreams, wherein she adopts the alter-ego "Paprika". When the device is stolen, she must stop rogue elements from merging the dream and waking worlds.
In 2027, in a chaotic world in which humans can no longer procreate, a former activist agrees to help transport a miraculously pregnant woman to a sanctuary at sea, where her child's birth may help scientists save the future of humankind.